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Aprepitant is used to treat vomiting caused by chemotherapy. Aprepitant blocks the action of substance P by binding to NK-1 receptors (mainly present in the central nervous system and its peripherals), and can occupy NK-1 receptors in the brain through the blood-brain barrier, with selectivity and high affinity, while the affinity for NK-2 and NK-3 receptors is low.
Items | Specifications | Results |
Appearance | White to off-white powder | Off-white powder |
Desfluoro aprepitant | ≤0.1% | 0.05% |
Any single impurity | ≤0.1% | 0.06% |
Total impurities | ≤0.3% | 0.18% |
Enantiomer | ≤0.1% | 0.07% |
Assay | 98.0%~102.0% | 100.1% |
Product parameters | |
Cas number: | 170729-80-3 |
Appearance: | White to off-white powder |
Purity: | 99~102% |
Package details: | 100g/bottle; 1kg/foil bag |
Brand: | Fortunachem |
Aprepitant is a neurokinin-1 (NK-1) receptor antagonist. It is an anticancer chemotherapy vomiting agent.
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