Benfotiamine CAS 22457-89-2 Wholesale & Bulk

Name: Benfotiamine CAS 22457-89-2
Brand: Wuhan Fortuna Chemical Co., Ltd.

Benfotiamine is mainly used in the treatment of diabetic complications. Benfotiamine alleviates diabetic complications (such as neuropathy, nephropathy, and retinopathy) by inhibiting the formation of advanced glycation end products (AGE). Benfotiamine increases TPP in tissues, which enhances the activity of transketolases to reduce AGE in tissues and ultimately inhibit the progression of diabetic complications. The effects of benfotiamine also include improving diabetic myocardial contractility, reducing neuropathic pain and improving ventricular dysfunction after ischemia.

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Specifications of Benfotiamine CAS 22457-89-2

ITEMS	SPECIFICATIONS	RESULTS
Appearance	White crystal or white crystalline powder	Conform
Identification	The retention time of main peak is accordant with that of Benfotiamine RS	Conform
Melting point	≥198℃	203~206℃
Loss on drying	≤1.2%	0.4%
Clarity and color of solution	Colorless to light yellow clear solution	Colorless and clear solution
Chloride	≤0.053%	<0.053%
Sulphate	≤0.011%	<0.011%
Heavy metals	≤20ppm	<20ppm
Cd	≤1ppm	0.042ppm
As	≤1ppm	<0.01ppm
Pb	≤0.5ppm	<0.02ppm
Hg	≤0.3ppm	<0.005ppm
Bulk density	≥0.35g/ml	0.50g/ml
Related substances	Thiamine ≤0.1%	0.09%
	Benzoic acid ≤0.1%	0.01%
	Total impurities ≤1.0%	0.3%
Microbe. Test:	Total Plate Count ≤1000CFU/g	＜10CFU/g
	Yeast & Mold≤100CFU/g	＜10CFU/g
	Salmonella Negative	Negative
	E.Coli Negative	Negative
	StaphylococcusAureus	Negative
Assay	98.0%～ 102.0%	100.8%
Conclusion	QUALIFIED.