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Antineoplastics API


Antineoplastics drugs are drugs that inhibit or kill tumor cells in the body. It plays an important role in the comprehensive treatment of tumors, especially for the treatment of leukemia and spread tumors that cannot be surgically treated.

Types Of Antineoplastics API


Chemical Name CAS MF
Gemcitabine hydrochloride CAS 122111-03-9

Gemcitabine hydrochloride

122111-03-9

C9H12ClF2N3O4

Oxaliplatin CAS 61825-94-3

Oxaliplatin

61825-94-3

C8H14N2O4Pt

Ibrutinib CAS 936563-96-1

Ibrutinib

936563-96-1

C25H24N6O2

Phenethyl caffeate CAS 104594-70-9

Phenethyl caffeate

104594-70-9

C17H16O4

Dacarbazine CAS 4342-03-4

Dacarbazine

4342-03-4

C6H10N6O

Bortezomib CAS 179324-69-7

Bortezomib

179324-69-7

C19H25BN4O4

Pirfenidone CAS 53179-13-8

Pirfenidone

53179-13-8

C12H11NO

Everolimus CAS 159351-69-6

Everolimus

159351-69-6

C53H83NO14

Dabrafenib CAS 1195765-45-7

Dabrafenib

1195765-45-7

Features Of Antineoplastics API

Anti-tumor drugs are currently used, mostly by inhibiting DNA or RNA synthesis, or even destroying DNA structure. According to the effect on tumor cells in each stage, there are two categories of cell cycle-specific drugs and cell cycle non-specific drugs. Although the effects of the two drugs are not the same, but the bone marrow hematopoietic stem cells and other cells with short growth cycle have the same degree of lethal effect, and can inhibit the body's immune response.

Features Of Antineoplastics API

Regulations Of Antineoplastics API

1. Must be carried out in the area/environment with dust control measures, dust control measures include but are not limited to: negative pressure weighing cover, exhaust gas absorption system, isolation operator, of which the most preferably isolating operator.

2. As far as possible to reduce the exposure of materials / products, should be sealed for material / product addition, transfer, including but not limited to: double valve barrels, laminated trolleys and so on.

3. For the presence of material exposure may be areas, dust occupational exposure limit monitoring, monitoring must be carried out by third parties.

4. Anti-tumor drugs cross-contamination daily monitoring, monitoring points based on human flow, logistics channels, exhaust lines and other assessment, can be used on the door, window, exhaust pipe surface wipe sampling to detect drug residue to confirm whether there is diffusion.

Of course, regular work clothes, hard hats, and fully protective gas masks are all to be configured.

Regulations Of Antineoplastics API
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