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Bis(trifluoroacetoxy)iodobenzene, often abbreviated as BTI, is a powerful and versatile reagent used in organic synthesis. It consists of an iodine atom bound to a benzene ring, with two trifluoroacetate (CF3COO) groups attached to the iodine atom. This compound is a highly electrophilic iodinating agent, meaning it readily transfers iodine atoms to other molecules.
BTI is commonly employed in various synthetic transformations, such as the conversion of alcohols to iodides, the synthesis of aryl iodides from aryl sulfonates, and the preparation of α-iodo ketones from ketones, among other reactions. Its trifluoroacetate leaving groups enhance its reactivity and stability compared to other iodine-based reagents.
Overall, BTI is valued for its efficiency, selectivity, and mild reaction conditions, making it a valuable tool in organic chemistry research and industrial applications.
Description of [Bis(trifluoroacetoxy)iodo]benzene from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of [Bis(trifluoroacetoxy)iodo]benzene | |
Product Name | [Bis(trifluoroacetoxy)iodo]benzene |
CAS NO. | 2712-78-9 |
Apperance | White crystalline powder |
Assay | 99.73% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of High Purity 99.73% Pharmaceutical Intermediate [Bis(trifluoroacetoxy)iodo]benzene CAS NO 2712-78-9
Items | Specifications | Results |
Appearance | White crystalline powder | Conforms |
Purity | ≥98% | 99.73% |
Melting Point | 121-126℃ | 122.2-122.9% |
Conclusion | The product conforms to the standard of CP2010. |
Introduction of [Bis(trifluoroacetoxy)iodo]benzene.
Bis(trifluoroacetoxy)iodobenzene, often abbreviated as BTI, is a powerful and versatile reagent used in organic synthesis. It consists of an iodine atom bound to a benzene ring, with two trifluoroacetate (CF3COO) groups attached to the iodine atom. This compound is a highly electrophilic iodinating agent, meaning it readily transfers iodine atoms to other molecules.
BTI is commonly employed in various synthetic transformations, such as the conversion of alcohols to iodides, the synthesis of aryl iodides from aryl sulfonates, and the preparation of α-iodo ketones from ketones, among other reactions. Its trifluoroacetate leaving groups enhance its reactivity and stability compared to other iodine-based reagents.
Overall, BTI is valued for its efficiency, selectivity, and mild reaction conditions, making it a valuable tool in organic chemistry research and industrial applications.
Application of [Bis(trifluoroacetoxy)iodo]benzene.
Bis(trifluoroacetoxy)iodobenzene (BTI) finds wide application in organic synthesis due to its powerful iodinating properties. Some of its key applications include:
1. Halogenation Reactions: BTI is commonly used for the selective halogenation of aromatic compounds. It can introduce iodine atoms onto aromatic rings, facilitating further functionalization or providing access to specific intermediates.
2. Oxidation Reactions: BTI can act as an oxidizing agent in various transformations. For instance, it can oxidize alcohols to aldehydes or ketones, or convert sulfides to sulfoxides or sulfones.
3. Halogen Exchange Reactions: BTI can facilitate halogen exchange reactions, enabling the substitution of one halogen atom with another in organic molecules. This is particularly useful in synthetic chemistry for modifying functional groups.
4. Functional Group Transformations: BTI can participate in a variety of functional group transformations, including the conversion of alcohols to iodides, the synthesis of α-iodo ketones from ketones, and the preparation of aryl iodides from aryl sulfonates.
5. C—H Functionalization: BTI can activate aromatic C—H bonds, enabling the direct functionalization of aromatic compounds at specific positions. This approach offers a streamlined route to complex molecules and pharmaceutical intermediates.
6. Total Synthesis: BTI is often utilized in the total synthesis of natural products and pharmaceuticals, where its selective and efficient reactivity enables the construction of complex molecular frameworks.
Overall, the versatility and efficacy of BTI make it a valuable tool in organic synthesis, enabling chemists to access a wide range of functionalized molecules and complex structures efficiently.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide [Bis(trifluoroacetoxy)iodo]benzene with good quality and best price, welcome to contact us to get COA/TDS/MSDS of [Bis(trifluoroacetoxy)iodo]benzene.
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