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Introduction of TSTU.
TSTU stands for N,N,N’,N’-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate. It is a chemical reagent commonly used in organic synthesis, particularly in peptide coupling reactions. TSTU is employed to activate carboxyl groups, facilitating the formation of amide bonds between carboxylic acids and amines. This makes it a valuable tool in the synthesis of peptides and other amide-containing compounds.
The reagent is known for its efficiency and mild reaction conditions, which help in minimizing side reactions and degradation of sensitive molecules. It is often preferred in peptide synthesis due to its ability to produce high yields and its compatibility with a wide range of functional groups.
Description of TSTU from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of TSTU | |
Product Name | TSTU |
CAS NO. | 105832-38-0 |
Apperance | White crystalline powder |
Assay | 99.9% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Factory Direct Supply TSTU CAS 105832-38-0 with High Quality Pharmaceutical Intermediate for Peptide
Items | Specifications | Results |
Appearance | White crystalline powder | Complies |
Purity (HPLC) | ≥99.0% | 99.9% |
Melting point | 196.0-205.0°C | 196.4- 198.0°C |
Clarity of the solution | 1g in 10ml acetonitrile,clear | Complies |
Loss on drying | ≤0.5% | 0.21% |
Conclusion | The product conforms to the standard of CP2010. | |
Introduction of TSTU.
TSTU stands for N,N,N’,N’-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate. It is a chemical reagent commonly used in organic synthesis, particularly in peptide coupling reactions. TSTU is employed to activate carboxyl groups, facilitating the formation of amide bonds between carboxylic acids and amines. This makes it a valuable tool in the synthesis of peptides and other amide-containing compounds.
The reagent is known for its efficiency and mild reaction conditions, which help in minimizing side reactions and degradation of sensitive molecules. It is often preferred in peptide synthesis due to its ability to produce high yields and its compatibility with a wide range of functional groups.
Application of TSTU.
TSTU (N,N,N’,N’-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate) is primarily used in organic synthesis, with its most notable application being in peptide coupling reactions. Here are some specific applications of TSTU:
Peptide Synthesis: TSTU is widely used to facilitate the formation of amide bonds between carboxylic acids and amines, which is a crucial step in the synthesis of peptides. It activates the carboxyl group of amino acids, making it more reactive towards nucleophilic attack by the amine group of another amino acid.
Amide Bond Formation: Beyond peptides, TSTU is also used to form amide bonds in the synthesis of various organic compounds, including pharmaceuticals, natural products, and polymers.
Protein Modification: TSTU can be used to modify proteins by coupling carboxyl groups on the protein with amines, which can be useful in bioconjugation and the development of protein-based therapeutics.
Solid-Phase Synthesis: In solid-phase peptide synthesis (SPPS), TSTU is used to activate the carboxyl groups of amino acids that are attached to a solid support, facilitating the stepwise construction of peptides.
Macrocycle Synthesis: TSTU can be employed in the synthesis of macrocyclic compounds, which are important in medicinal chemistry for the development of drugs with specific biological activities.
Polymer Chemistry: In polymer chemistry, TSTU can be used to create functionalized polymers by coupling carboxyl-containing monomers with amine-containing monomers.
Drug Development: TSTU is used in the synthesis of various drug candidates, particularly those that require the formation of stable amide bonds.
Overall, TSTU is valued for its efficiency, mild reaction conditions, and compatibility with a wide range of functional groups, making it a versatile reagent in both academic and industrial chemical research.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide TSTU with good quality and best price, welcome to contact us to get COA/TDS/MSDS of TSTU.
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