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Deoxycorticosterone acetate (DOCA) is a synthetic steroid hormone. It's a derivative of the naturally occurring hormone aldosterone, which is produced in the adrenal glands and plays a key role in regulating electrolyte and fluid balance in the body, particularly by increasing the reabsorption of sodium ions and water and by excreting potassium ions.
DOCA has been used in medical settings for its mineralocorticoid effects, particularly in experimental studies of hypertension and kidney function. It has also been used in certain medical treatments, although its clinical use has declined over the years due to the availability of more specific and effective drugs.
Description of Deoxycorticosterone acetate from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Deoxycorticosterone acetate | |
Product Name | Deoxycorticosterone acetate |
CAS NO. | 56-47-3 |
Apperance | White crystalline powder |
Assay | 99.1% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Factory Supply Active Pharmaceutical Ingredient Deoxycorticosterone acetate CAS NO 56-47-3 High Assay 99.1%
Items | Specifications | Results |
Appearance | A white or almost white crystalline powder | White crystalline powder |
Identification | A: Infrared Absorption<197K>B: Ultraviolet Absorption<197U> | Complies |
Melting range | 155℃ to 161℃ | 159℃ to 160℃ |
Specific rotation | + 171° to + 179° | + 176° |
Loss on drying | 0.5% Max. | 0.14% |
Related substances | Individual impurity: 0.5% Max. Total impurities: 1.0% Max. | 0.16% 0.7% |
Assay | 97.0% to 103.0% | 99.1% |
Conclusion | QUALIFIED. | |
Introduction of Deoxycorticosterone acetate.
Deoxycorticosterone acetate (DOCA) is a synthetic steroid hormone. It's a derivative of the naturally occurring hormone aldosterone, which is produced in the adrenal glands and plays a key role in regulating electrolyte and fluid balance in the body, particularly by increasing the reabsorption of sodium ions and water and by excreting potassium ions.
DOCA has been used in medical settings for its mineralocorticoid effects, particularly in experimental studies of hypertension and kidney function. It has also been used in certain medical treatments, although its clinical use has declined over the years due to the availability of more specific and effective drugs.
Application of Deoxycorticosterone acetate.
Deoxycorticosterone acetate (DOCA) has been used in various medical applications, primarily due to its mineralocorticoid properties. Some of its historical and current applications include:
Experimental Studies: DOCA has been extensively used in experimental studies, particularly in animal models, to investigate hypertension, kidney function, and electrolyte balance. Researchers have used DOCA to induce hypertension in animals for studying its mechanisms and potential treatments.
Treatment of Adrenal Insufficiency: In the past, DOCA has been used as a replacement therapy for adrenal insufficiency (Addison's disease). However, its use for this purpose has largely been replaced by more specific glucocorticoid and mineralocorticoid replacements.
Research Tool: DOCA is often used as a research tool in laboratory studies to manipulate mineralocorticoid levels and study their effects on various physiological processes, such as kidney function, blood pressure regulation, and electrolyte balance.
Animal Models of Hypertension: DOCA has been used to induce hypertension in animal models for studying the pathophysiology of hypertension and testing potential therapeutic interventions.
Studying Salt Sensitivity: DOCA has been used to induce salt-sensitive hypertension in animal models, allowing researchers to study the mechanisms underlying salt sensitivity and its relationship to hypertension and cardiovascular disease.
Overall, while DOCA has been valuable in research settings for studying various aspects of physiology and disease, its clinical use has diminished over time due to the availability of more specific and effective drugs for treating conditions such as adrenal insufficiency and hypertension.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Deoxycorticosterone acetate with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Deoxycorticosterone acetate.
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