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Neo Heliopan AP (INCI: Disodium Phenyl Dibenzimidazole Tetrasulfonate) is a water-soluble organic UVA II sunscreen filter developed by Symrise AG (Germany). It absorbs UV light in the 320–370 nm range with a peak at 335 nm.
Key Selling Points:
Water-soluble — enables transparent gels, clear sprays, and oil-free sunscreens
Highly photostable — no degradation under sunlight
Synergistic SPF boost — enhances SPF when paired with oil-soluble UVB filters
Excellent safety — extremely low skin penetration
Broad regulatory approval — EU, China, Brazil, South Korea, ASEAN (up to 10%)
Main Uses: Sunscreens (gels, sprays, fluids), daily anti-aging moisturizers with SPF, sensitive skin and children's sun care, and oil-free formulations for acne-prone skin.
Description of Neo Heliopan AP from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Neo Heliopan AP | |
Product Name | Neo Heliopan AP |
CAS NO. | 180898-37-7 |
Apperance | yellow to dark yellow |
Assay | 99.64% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Manufacturer high quality Neo Heliopan AP Powder CAS NO 180898-37-7 Other Fine Chemicals With Good Price
Items | Specifications | Results |
Lot No | ---- | 0901240318007 |
Color | yellow to dark yellow | yellow to dark yellow |
Appearance | powder | powder |
Loss on Drying | 3.0%max | 0.59 |
Purity by HPLC | 96.0%min | 99.64 |
Extinction(E1%,1cm) | 770min | 785 |
M.D. | ---- | 240318 |
B.B.D. | ---- | 270317 |
Weight | g | 500 |
Conclusion | The product conforms to the standard of CP2010. | |
Neo Heliopan AP is a water-soluble, organic UVA II chemical sunscreen filter developed and marketed by Symrise AG (Germany). Its INCI name is Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), and its USAN designation is Bisdisulizole Disodium. The molecular formula is C₂₀H₁₂N₄Na₂O₁₂S₄, with a molecular weight of 674.57 g/mol and CAS number 180898-37-7.
Structurally, Neo Heliopan AP is built on a bis-benzimidazole core — two benzimidazole rings linked by a central phenylene (benzene) bridge — with four sulfonate groups (–SO₃⁻) attached to the benzimidazole rings. These sulfonate groups are what confer its distinctive water solubility, setting it apart from the vast majority of UV filters that are oil-soluble. The compound forms water-soluble salts upon addition of a base (typically sodium hydroxide or triethanolamine).
It appears as a yellow fine powder, is hygroscopic, and exhibits strong UV absorption in the UVA II range (320–370 nm) with a peak absorbance at 335 nm and a molar extinction coefficient of at least 770–800 (1%/1 cm) in water. Its LogP value of approximately –2 to –4 confirms its strongly hydrophilic character.
Neo Heliopan AP was first approved for use as a UV filter in the European Union in 2000, and has since been approved in Brazil, South Africa (2000), South Korea (2004), China, ASEAN countries, and other markets. Notably, it is not approved by the U.S. FDA for use in over-the-counter sunscreen products.
Key Selling Points
1. Water Solubility — Unique Formulation Advantage
The most distinctive feature of Neo Heliopan AP is its water solubility. The overwhelming majority of organic UV filters (avobenzone, octocrylene, octinoxate, etc.) are oil-soluble. Neo Heliopan AP dissolves in the aqueous phase of a formulation, enabling formulators to create water-based, transparent, non-greasy sunscreen products such as gels, clear sprays, and light fluids that are impossible to achieve with oil-soluble filters alone.
2. Exceptional Photostability
Neo Heliopan AP is highly photostable — it does not degrade upon exposure to sunlight. This ensures consistent, long-lasting UVA protection throughout sun exposure and gives it a significant advantage over photolabile filters like avobenzone, which can lose up to 50–90% of its absorption capacity without photostabilizers.
3. Synergistic SPF Boosting with Oil-Soluble UVB Filters
When combined with oil-soluble UVB filters (such as octocrylene, octinoxate, or ethylhexyl salicylate), Neo Heliopan AP demonstrates synergistic effects, meaning the combined SPF is greater than the sum of individual contributions. This allows formulators to achieve higher SPF values with lower total filter loads.
4. Broad-Spectrum UVA Coverage When Paired with UVA I Filters
Neo Heliopan AP covers the UVA II band (320–350 nm). When combined with a UVA I absorber such as Neo Heliopan® 357 (butyl methoxydibenzoylmethane/avobenzone) or Uvinul A Plus, it enables formulation of very broad-spectrum UVA protection covering the full 320–400 nm range.
5. Excellent Safety Profile — Extremely Low Skin Penetration
Studies have demonstrated that Neo Heliopan AP has extremely low skin penetration due to its high molecular weight (674.57 g/mol) and strong hydrophilicity (LogP ≈ –2 to –4). The molecule is too large and too water-soluble to effectively cross the stratum corneum, resulting in minimal systemic exposure. The SCCNFP (Scientific Committee on Cosmetic and Non-Food Products) has evaluated its toxicological data and considered it safe for use in cosmetic formulations.
6. Compatibility with Ingredients and Packaging
Neo Heliopan AP is compatible with a wide range of cosmetic ingredients and packaging materials. It is non-corrosive and does not interact adversely with common formulation components, making it straightforward to incorporate into existing product lines.
7. Regulatory Approval Across Major Markets
Approved at up to 10% (as acid) in the EU, Brazil, South Africa, South Korea, China, and ASEAN countries — covering the vast majority of the global sunscreen market outside the United States.
Major Uses & Applications
☀️ Sunscreen & Sun Care Products (Primary Application)
Neo Heliopan AP's primary and most important use is as a UVA II filter in sunscreen formulations. It is incorporated into a wide range of product types:
Water-based transparent gels — its water solubility allows clear, non-whitening gel formulations that are popular for body and sport sunscreens
Clear spray sunscreens — enables alcohol- or water-based transparent spray formats
Lightweight fluid sunscreens — contributes UVA protection without adding oil-phase burden, enabling ultra-light, non-greasy textures
High-SPF broad-spectrum sunscreens — works synergistically with UVB filters and UVA I filters to achieve SPF 50+ and high UVA-PF ratings
Water-resistant / sport sunscreens — its water-soluble nature means it distributes in the aqueous phase and can help maintain a more uniform protective film on skin, especially in sweat-resistant formulations
Daily Wear & Anti-Aging Products
Day creams and moisturizers with SPF — provides UVA protection in daily-use products targeting photoaging prevention
Anti-aging and anti-wrinkle products — UVA rays are the primary drivers of extrinsic skin aging (photoaging); Neo Heliopan AP helps protect against collagen degradation, elastin damage, and wrinkle formation caused by UVA exposure
BB/CC creams and tinted moisturizers — can be incorporated into the water phase of emulsion-based color cosmetics with SPF
👶 Sensitive Skin & Children's Sun Care
Due to its extremely low skin penetration and excellent safety profile, Neo Heliopan AP is considered suitable for sensitive skin formulations and children's sunscreens, where minimizing percutaneous absorption is a priority. However, some regulatory guidance notes that data on infant skin exposure remains limited, and formulators should consider this when targeting very young age groups.
💧 Oil-Free & Acne-Prone Skin Formulations
Its water solubility makes it ideal for oil-free sunscreen products designed for acne-prone or oily skin types. By residing in the aqueous phase, it provides UVA protection without contributing to the oil phase or clogging pores — a significant advantage over oil-soluble UVA filters like avobenzone.
🏭 Industrial & Pharmaceutical Applications
Used as a photoprotective agent in topical pharmaceutical formulations
Serves as a light stabilizer in cosmetic and personal care products beyond sunscreens, protecting product integrity from UV degradation
Used as a chemical reagent and pharmaceutical intermediate in research settings
Regulatory Status Summary
| Market | Status | Max Concentration |
|---|---|---|
| European Union | ✅ Approved since 2000 | 10% (as acid) |
| China | ✅ Approved (Cosmetic Safety Technical Standard, Item 11) | 10% (as acid) |
| Brazil (ANVISA) | ✅ Approved | 10% |
| South Africa | ✅ Approved since 2000 | 10% |
| South Korea | ✅ Approved since 2004 | No upper limit (registration required) |
| ASEAN | ✅ Approved | Varies |
| Australia | ✅ Approved | Listed in TGA database |
| United States (FDA) | ❌ Not approved | N/A |
| ✅ Compatible With | ⚠️ Considerations |
|---|---|
| Oil-soluble UVB filters (octocrylene, octinoxate, homosalate) | Requires pH adjustment (forms salts with bases) |
| UVA I filters (avobenzone, Uvinul A Plus) | Hygroscopic — requires moisture-controlled storage |
| Most emulsifiers and thickeners | Not compatible with very low pH systems (< 4) |
| Most preservative systems | Water phase only — cannot be dissolved in oil phase |
| Alcohol-based systems | May show fluorescence under UV light |
| Selling Point | Detail |
|---|---|
| Water solubility | Enables transparent gels, clear sprays, oil-free sunscreens |
| UVA II absorption | Peak at 335 nm, covers 320–370 nm |
| High extinction coefficient | ≥770–800 (1%/1 cm) — strong absorption per unit |
| Photostability | Highly stable under UV exposure — no degradation |
| Synergistic SPF boost | Enhances SPF when combined with oil-soluble UVB filters |
| Safety profile | Extremely low skin penetration, SCCNFP-evaluated as safe |
| Regulatory coverage | Approved in EU, China, Brazil, South Korea, ASEAN, and more |
| Max use level | Up to 10% (as acid) |
In short, Neo Heliopan AP's core competitive advantage is its unique water solubility among UVA filters, which opens formulation possibilities that oil-soluble UVA filters simply cannot match — transparent gels, clear sprays, lightweight fluids, and oil-free sunscreens — while delivering highly photostable, broad UVA II protection with an excellent safety profile and synergistic SPF enhancement when combined with complementary filters. It is the go-to UVA II filter for formulators seeking water-phase UV protection in modern, aesthetically elegant sun care products.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Neo Heliopan AP with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Neo Heliopan AP.
1. Guaranteed purity;
2. Large quantity in stock;
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4. Best service after shipment with email;
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