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Introduction of Lanosterol.
Lanosterol is a sterol, a type of organic molecule that is a key intermediate in the biosynthesis of steroids. It is a crucial component in the cholesterol synthesis pathway in animals and the ergosterol synthesis pathway in fungi. Here are some key points about lanosterol:
1. Chemical Structure: Lanosterol has the chemical formula C30H50O and is characterized by a tetracyclic ring system. It is derived from squalene through a complex cyclization process.
2. Biosynthesis: Lanosterol is synthesized from squalene via a reaction catalyzed by the enzyme squalene epoxidase, which converts squalene into squalene epoxide. This is followed by cyclization through lanosterol synthase, resulting in the formation of lanosterol.
3. Role in Steroidogenesis: Lanosterol is a key intermediate in the biosynthetic pathway of steroids. In animals, it is converted into cholesterol through a series of enzyme-catalyzed steps. Cholesterol is a vital component of cell membranes and a precursor for the synthesis of steroid hormones, bile acids, and vitamin D.
4. Health and Medical Research: Lanosterol has garnered interest in medical research, particularly for its potential role in treating cataracts. Some studies have suggested that lanosterol can help dissolve the protein aggregates that cause cataracts, potentially offering a non-surgical treatment option.
5. Fungal Steroid Pathway: In fungi, lanosterol is converted into ergosterol, which is an essential component of fungal cell membranes and a target for antifungal drugs.
Lanosterol’s importance spans multiple biological processes, making it a significant molecule in both health and disease contexts.
Description of Lanosterol from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Lanosterol | |
Product Name | Lanosterol |
CAS NO. | 79-63-0 |
Apperance | White powder |
Assay | 98% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Cosmetic Raw Materials Pure Lanosterol Powder for Eye Drops CAS NO 79-63-0 in Stock
Items | Specifications | Results |
Appearance | White powder | Conforms |
Melting Point | 135-138℃ | 137℃ |
Purity by HPLC | ≥60% | 63.10% |
Loss on Drying | ＜1.5% | 0.9% |
Conclusion | The product conforms to the standard of CP2010. | |
Introduction of Lanosterol.
Lanosterol is a sterol, a type of organic molecule that is a key intermediate in the biosynthesis of steroids. It is a crucial component in the cholesterol synthesis pathway in animals and the ergosterol synthesis pathway in fungi. Here are some key points about lanosterol:
1. Chemical Structure: Lanosterol has the chemical formula C30H50O and is characterized by a tetracyclic ring system. It is derived from squalene through a complex cyclization process.
2. Biosynthesis: Lanosterol is synthesized from squalene via a reaction catalyzed by the enzyme squalene epoxidase, which converts squalene into squalene epoxide. This is followed by cyclization through lanosterol synthase, resulting in the formation of lanosterol.
3. Role in Steroidogenesis: Lanosterol is a key intermediate in the biosynthetic pathway of steroids. In animals, it is converted into cholesterol through a series of enzyme-catalyzed steps. Cholesterol is a vital component of cell membranes and a precursor for the synthesis of steroid hormones, bile acids, and vitamin D.
4. Health and Medical Research: Lanosterol has garnered interest in medical research, particularly for its potential role in treating cataracts. Some studies have suggested that lanosterol can help dissolve the protein aggregates that cause cataracts, potentially offering a non-surgical treatment option.
5. Fungal Steroid Pathway: In fungi, lanosterol is converted into ergosterol, which is an essential component of fungal cell membranes and a target for antifungal drugs.
Lanosterol’s importance spans multiple biological processes, making it a significant molecule in both health and disease contexts.
Application of Lanosterol.
Lanosterol has several notable applications, particularly in the fields of medical research and biotechnology:
1. Potential Treatment for Cataracts:
- Non-Surgical Cataract Treatment: Lanosterol has been investigated for its potential to dissolve the protein aggregates that form cataracts in the lens of the eye. Some studies have shown that lanosterol eye drops can reduce the opacity of cataracts, which could lead to a non-surgical treatment option for this common condition.
2. Cholesterol Biosynthesis Research:
- Cholesterol Pathway Studies: Lanosterol is a key intermediate in the biosynthesis of cholesterol. Research involving lanosterol can help scientists understand the regulation and function of cholesterol metabolism, which is crucial for developing treatments for hypercholesterolemia and other cholesterol-related disorders.
3. Antifungal Research:
- Ergosterol Synthesis Inhibition: In fungi, lanosterol is a precursor to ergosterol, an essential component of fungal cell membranes. Understanding this pathway is vital for developing antifungal drugs that target ergosterol biosynthesis, thereby inhibiting fungal growth.
4. Steroid Hormone Production:
- Steroidogenesis Studies: Lanosterol is a precursor in the biosynthesis of steroid hormones. Research in this area can lead to a better understanding of hormone production and the development of therapeutic agents for hormonal disorders.
5. Biotechnological Applications:
- Synthetic Biology: Lanosterol and its derivatives can be used in synthetic biology for the engineered production of various sterols and steroids. This has potential applications in pharmaceuticals, agriculture, and industrial biotechnology.
6. Cosmetic Industry:
- Skincare Products: Lanosterol has been explored for use in skincare products due to its potential benefits for skin health. It may contribute to skin hydration and barrier function, although this application is less common compared to its medical research uses.
7. Neurodegenerative Disease Research:
- Protein Aggregation Studies: Given its potential to dissolve protein aggregates in cataracts, lanosterol is also being investigated for its effects on protein aggregation in neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. This research is still in early stages but holds promise for future therapeutic developments.
Overall, while lanosterol’s primary applications are currently in research and potential therapeutic development, its role in critical biological pathways underscores its importance in both health and disease contexts.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Lanosterol with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Lanosterol.
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