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2'-Deoxy-L-thymidine is an HBV reverse transcriptase inhibitor used to treat hepatitis B infections.
2'-Deoxy-L-thymidine is a synthetic thymine deoxynucleoside drug against hepatitis B virus DNA polymerase. 2'-Deoxy-L-thymidine is phosphorylated to the active metabolite adenosine under the action of cytokinase, which inhibits the activity of hepatitis B virus DNA polymerase by competing with thymine 5′-adenosine, a natural substrate in hepatitis B virus; By integrating into the hepatitis B virus DNA, it causes the hepatitis B virus DNA strand to be prolonged and terminated. It simultaneously inhibits the synthesis of the first and second strands of hepatitis B virus DNA. It is indicated for the treatment of adult patients with chronic hepatitis B who have evidence of hepatitis B virus activity replication and are compensated for liver function with persistently elevated aminotransferases or active lesions of the liver.
Items | Specification | Result |
Assay | ≥ 99.5% | 99.91% |
Appearance | white fine powder | Conforms |
Loss on drying | ≤0.5% | 0.11% |
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Product parameters | |
Cas number: | 3424-98-4 |
Appearance: | white fine powder |
Purity: | 99.5%min |
Package details: | 10g/aluminium foil bag;25kg/drum |
Brand: | Fortunachem |
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