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Glibenclamide is mainly used to treat mild and moderate non-insulin-dependent diabetes mellitus. Glibenclamide can selectively act on pancreatic β cells, promote insulin secretion, enhance the hypoglycemic effect of exogenous insulin, and strengthen the receptor effect of insulin. Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.
Items | Specification | Result |
Assay | ≥99% | 99.8% |
Apperance | White crystalline powder | White crystalline powder |
Loss on drying | ≤0.5% | 0.3% |
Residue on ignition | ≤0.1% | <0.1% |
Heavy metals | ≤10ppm | <10ppm |
Product parameters | |
Cas number: | 10238-21-8 |
Appearance: | White crystalline powder |
Purity: | 99%min |
Package details: | 1kg/foil bag;25kg/drum |
Brand: | Fortunachem |
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