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Ibrutinib is used to treat chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). Ibrutinib is a small molecule BTK inhibitor, which can selectively covalently bind to cysteine residues (Cys-481) on the active site of BTK, irreversibly inhibit the activity of BTK, thereby inhibit the activation of BCR signaling pathway, effectively prevent tumor migration from B cells to lymphoid tissues suitable for tumor growth, reduce the malignant proliferation of B cells and induce apoptosis of cells, thereby playing a role in the treatment of CLL and MCL.
Items | Specification | Result |
Assay | 98.0%-102.0% | 99.7% |
Purity | ≥99% | 99.8% |
Apperance | Greyish-white to white solid | Conforms |
Any single unknown impurity | ≤0.1% | 0.06% |
Product parameters | |
Cas number: | 936563-96-1 |
Appearance: | Greyish-white to white solid |
Purity: | 99%min |
MOQ: | 10g |
Price: | Negotiable |
Package details: | 10g,100g,1kg/foil bag |
Brand: | Fortunachem |
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