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Introduction of icodextrin.
Icodextrin is a complex, water-soluble glucose polymer derived from cornstarch. It is primarily used in medical applications, particularly in peritoneal dialysis solutions. In this context, icodextrin serves as an osmotic agent to help remove excess fluid and waste products from the blood when the kidneys are not functioning properly. It works by creating an osmotic gradient that draws fluid into the peritoneal cavity, where it can then be drained away.
Icodextrin is particularly useful for patients undergoing long-dwell peritoneal dialysis, such as during overnight treatments, because it provides sustained osmotic activity over an extended period. This can be beneficial for patients who have difficulty achieving adequate fluid removal with standard glucose-based dialysis solutions.
Description of icodextrin from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of icodextrin | |
Product Name | icodextrin |
CAS NO. | 337376-15-5 |
Apperance | White to beige powder |
Assay | 98%min |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Factory Supply Icodextrin Powder CAS 337376-15-5 for Peritoneal Dialysis Solutions / Skin Care
Items | Specifications | Results |
Appearance | White to beige powder | Conforms |
Specific Rotation | +190°～ +200° | +197° |
Solubility (g/L) | ≥200 | Conforms |
Identification | The solution reacts with iodine test solution,color become blue to reddish brown. | Conforms |
The solution reacts with alkaline copper tartrate test solution,produce red | Conforms | |
pH (25℃) | 3.5～6.5 | 6.4 |
Clarity and color | Meet the requirements | Conforms |
Absorbance(400nm) | ≤0.05 | 0.003 |
5-Hydroxymethyl furfural (%) | ≤0.01 | 0.0005 |
Loss on drying (%) | ≤7.0 | 4.2 |
Heavy Metal (ppm) | ≤5 | ＜5 |
Peptidoglycan (ng/g) | ≤2 | 0.089 |
Nitrogen(%) | ≤0.01 | 0.005 |
Weight-average Molecular Weight (Mw) | 13000~19000 | 15252 |
Number-average molecular weight (Mn) | 5000~6500 | 5656 |
Molecular weight ≤1638 | ≤6% | 5.4 |
Molecular weight 1638~5000 | 12%~26% | 19.1 |
Molecular weight 5000~20000 | 45%~66% | 49.5 |
Molecular weight 20000~45000 | 13%~23% | 22.0 |
Molecular weight 1638~45000 | ≥85% | 90.6 |
Bacterial Endotoxins (EU/g) | ＜0.3 | ＜0.3 |
TAMC (CFU/g) | ≤50 | 10 |
TYMC (CFU/g) | ≤10 | ＜10 |
Escherichia Coli | Absent | Absent |
Conclusion | Comply with Enterprise Standard. | |
Introduction of icodextrin.
Icodextrin is a complex, water-soluble glucose polymer derived from cornstarch. It is primarily used in medical applications, particularly in peritoneal dialysis solutions. In this context, icodextrin serves as an osmotic agent to help remove excess fluid and waste products from the blood when the kidneys are not functioning properly. It works by creating an osmotic gradient that draws fluid into the peritoneal cavity, where it can then be drained away.
Icodextrin is particularly useful for patients undergoing long-dwell peritoneal dialysis, such as during overnight treatments, because it provides sustained osmotic activity over an extended period. This can be beneficial for patients who have difficulty achieving adequate fluid removal with standard glucose-based dialysis solutions.
Application of icodextrin.
Icodextrin is a glucose polymer used primarily in medical applications, particularly in peritoneal dialysis. Here are some of its key applications:
1. Peritoneal Dialysis:
Continuous Ambulatory Peritoneal Dialysis (CAPD): Icodextrin is used as an osmotic agent in peritoneal dialysis solutions. It helps to remove excess fluid and waste products from the blood when the kidneys are not functioning properly.
Automated Peritoneal Dialysis (APD): Similar to CAPD, icodextrin can be used in APD to enhance fluid removal over long dwell times, typically overnight.
2. Icodextrin Medical Cold Compress: This is a type of medical dressing that utilizes icodextrin. These dressings are often used for their cooling and soothing effects, which can help reduce inflammation and pain in various conditions, such as injuries, post-surgical recovery, and chronic pain management.
3. Wound Care:
Icodextrin can be used in wound care products to manage exudate and maintain a moist wound environment, which is conducive to healing.
4. Ophthalmic Surgery:
In some cases, icodextrin solutions are used during ophthalmic surgeries to maintain the shape of the eye and protect delicate tissues.
Mechanism of Action:
Icodextrin works by creating an osmotic gradient that draws fluid into the peritoneal cavity or the wound dressing. This helps in the removal of excess fluid and waste products in dialysis or in managing wound exudate.
In summary, icodextrin is a versatile medical polymer with applications in peritoneal dialysis, wound care, and medical dressings, including the icodextrin medical cold compresses for their cooling and soothing properties.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide icodextrin with good quality and best price, welcome to contact us to get COA/TDS/MSDS of icodextrin.
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