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Methyl sulfone(MSM) is an organic sulfide that is widely present in various organs and tissues such as bones, muscles, and skin of the human body. It is a raw material for the synthesis of human amino acids and is also a substance necessary for the synthesis of human collagen.
Methyl sulfone has the following effects: 1. It can eliminate viruses, strengthen blood circulation, soften tissues, reduce pain, strengthen muscles and bones, calm the spirit, enhance physical strength, maintain skin, hair and beauty, treat arthritis, mouth ulcers, asthma, constipation, transfusion of blood vessels, and remove toxins in the gastrointestinal tract. 2. Methyl sulfone can be used as a food and feed additive to supplement organosulfur nutrients for humans, pets and livestock. 3. Methyl sulfone can make the skin smooth, muscle soft, and reduce pigmentation, recently as a cosmetic additive dosage has increased sharply. 4. Methyl sulfone has good analgesia in medicine, promote wound healing and other functions. 5. Methyl sulfone is an excellent penetrant in the production of drugs.
Item | Specifications | Results |
Appearance | White crystal | Conform |
Residue on ignition | ≤0.2% | Conform |
Water | ≤0.2% | 0.15% |
Assay | ≥99.9% | 99.95% |
Product parameters | |
Cas number: | 67-71-0 |
Appearance: | White crystal |
Purity: | 99.9% min |
Package details: | 25kg/drum |
Brand: | Fortunachem |
Dimethyl sulfone (DMSO₂) is an organosulfur compound, naturally found in small amounts in many foods and beverages, and is also present in the human body. It is the oxidized form of Dimethyl sulfoxide (DMSO), a well-known industrial solvent.
Its most common commercial form is as a dietary supplement, often marketed for joint health. In its pure form, it appears as a white, crystalline, odorless powder.
You may also see it referred to by its common name: Methylsulfonylmethane, or more famously, MSM.
Chemical Formula: C₂H₆O₂S
Systematic Name: Methylsulfonylmethane
Molecular Structure: It consists of a sulfonyl functional group (S=O) attached to two methyl groups (-CH₃). The chemical formula is often written as (CH₃)₂SO₂.
Key Feature: It is a highly polar molecule, which contributes to its excellent solubility in water and some organic solvents.
Natural Sources: MSM is found naturally in small quantities in:
Green plants (like alfalfa, Equisetum/horsetail)
Fruits and vegetables (tomatoes, corn, apples)
Grains
Milk (from cows)
Coffee and tea
Production: While it can be isolated from natural sources, the MSM used in supplements is typically produced synthetically through the oxidation of DMSO. This industrial process ensures a high level of purity and consistent supply.
MSM is heavily marketed as a supplement with a wide range of benefits. However, it's crucial to distinguish between popular claims and what is supported by scientific evidence.
1. Joint Health and Osteoarthritis (Most Researched Use)
Claim: To reduce joint pain, stiffness, and inflammation associated with osteoarthritis (OA).
Evidence: Several clinical studies have shown that MSM supplementation (typically 1.5-6 grams per day) can lead to modest reductions in pain and improved physical function in people with OA of the knee. It is often studied in combination with glucosamine and chondroitin. The effect is generally considered mild to moderate.
2. Anti-inflammatory and Antioxidant
Claim: To reduce systemic inflammation and oxidative stress.
Evidence: Some animal and in vitro (test tube) studies suggest MSM can inhibit inflammatory cytokines and NF-κB (a key protein complex involved in inflammation). Human evidence for broad anti-inflammatory effects is less robust.
3. Exercise Recovery and Muscle Soreness
Claim: To reduce muscle damage and soreness (DOMS - Delayed Onset Muscle Soreness) after intense exercise.
Evidence: Results from studies are mixed. Some show a potential benefit in reducing markers of muscle damage and perceived soreness, while others show no significant effect.
4. Other Common Claims:
Allergies (e.g., hay fever): Limited evidence, with a few small studies suggesting a possible reduction in symptoms.
Skin, Hair, and Nail Health: Often added to topical creams and shampoos. Anecdotal reports suggest benefits for conditions like rosacea and brittle nails, but strong scientific evidence is lacking.
Snoring: Evidence is extremely limited and primarily anecdotal.
MSM is generally considered very safe and well-tolerated at recommended dosages (up to 4-6 grams per day).
Common Side Effects: Are typically mild and may include:
Digestive upset (nausea, diarrhea, bloating)
Headache
Difficulty sleeping (if taken close to bedtime)
Important Consideration: The quality and purity of supplements can vary. It is important to purchase from reputable sources.
Pregnancy and Breastfeeding: There is not enough reliable information to confirm its safety, so it is generally advised to avoid use.
Drug Interactions: No major interactions are well-documented, but it's always prudent to consult a healthcare provider before starting any new supplement, especially if you are on medication.
This is a critical distinction:
DMSO (Dimethyl sulfoxide) is primarily an industrial-grade solvent used in paint strippers, antifreeze, and as a veterinary anti-inflammatory. It is rapidly absorbed through the skin and can carry other substances with it. While it is approved for human use (as a prescription medication for a bladder condition called interstitial cystitis), non-pharmaceutical grade DMSO can contain dangerous impurities and is not safe for casual consumer use.
MSM (Dimethyl sulfone) is the oxidized, stable, and purified form of DMSO. It is the form the body metabolizes DMSO into. It is widely available and marketed as a dietary supplement.
Aspect | Description |
---|---|
What it is | An organosulfur compound, the oxidized form of DMSO. Also known as MSM. |
Natural Role | Found naturally in small amounts in many foods and in the human body. |
Primary Use | A dietary supplement primarily used for joint pain and inflammation in osteoarthritis. |
Chemical Formula | C₂H₆O₂S |
Safety Profile | Generally considered safe with mild side effects (digestive upset, headache). |
Key Distinction | Not the same as industrial solvent DMSO. MSM is the purified, supplemental form. |
Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new supplement.
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