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Spironolactone is used to treat high blood pressure and heart failure.
Spironolactone is a competitive inhibitor of aldosterone, the drug itself is not active, the diuretic effect is competitive antagonism with endogenous aldosterone, belongs to potassium-sparing diuretics. (1) Edema disease, which is combined with other diuretics to treat edematous diseases such as congestive heart failure, cirrhosis ascites, renal edema, etc., with the aim of correcting the secondary increased secretion of aldosterone associated with the above diseases and against the potassium excretion effect of other diuretics; It is also used in the treatment of idiopathic edema. (2) Hypertension, which is used as an adjuvant treatment for hypertension. (3) Primary aldosteronism, spironolactone can be used for the diagnosis and treatment of this disease. (4) Prevention of hypokalemia, which is combined with thiazide diuretics to enhance diuretic effect and prevent hypokalemia.
Item | Specifications | Results |
Appearance | White or almost white crystalline powder | Conform |
Loss on drying | ≤0.5% | 0.1% |
Assay | 97.0% - 103.0% | 100.9% |
Product parameters | |
Cas number: | 52-01-7 |
Appearance: | white or yellowish-white powder |
Purity: | 97.0% - 103.0% |
Package details: | 1kg/bag,25kg/drum |
Brand: | Fortunachem |
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