English 
Español 
français 
العربية Search
Search
5'-Deoxy-S-adenosyl-L-homocysteine (SAH) is a naturally occurring molecule that serves as a byproduct in the metabolism of methionine and is closely related to the compound S-adenosyl-L-methionine (SAM), an important methyl donor in biological reactions. Specifically, SAH is produced when SAM donates a methyl group in methylation reactions catalyzed by methyltransferase enzymes.
Description of 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE | |
Product Name | 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE |
CAS NO. | 979-92-0 |
Apperance | White powder |
Assay | 98% |
Package | 1g/bag |
Brand | Fortunachem |
5'-Deoxy-S-adenosyl-L-homocysteine (SAH) is a naturally occurring molecule that serves as a byproduct in the metabolism of methionine and is closely related to the compound S-adenosyl-L-methionine (SAM), an important methyl donor in biological reactions. Specifically, SAH is produced when SAM donates a methyl group in methylation reactions catalyzed by methyltransferase enzymes.
5'-Deoxy-S-adenosyl-L-homocysteine (SAH) has several applications primarily in biochemical research and diagnostics due to its role as a methyltransferase inhibitor and its involvement in methylation processes. Here are some key applications:
SAH as a Methyltransferase Inhibitor: SAH naturally inhibits methyltransferases, which are enzymes that add methyl groups to various substrates, including DNA and proteins. This inhibition makes it valuable for studying methylation patterns and understanding gene expression and epigenetic regulation.
Methylation Studies: By regulating the availability of SAH, researchers can explore the impact of methylation on different biological processes, such as cell differentiation, gene silencing, and cancer progression.
Cardiovascular Disease: Elevated levels of SAH are linked to increased cardiovascular risk because they indicate impaired methylation activity, which is associated with homocysteine accumulation—a risk factor for heart disease.
Cancer Biomarker: Changes in SAH levels are also studied as potential indicators of cancer, as altered methylation patterns are common in various cancers.
Liver Disease: Due to its role in methionine metabolism, SAH levels are also used in research on liver function and liver disease diagnostics.
Drug Target for Methylation-Related Disorders: SAH is studied as a target molecule to design drugs that modulate methylation. By influencing SAH levels, researchers aim to create therapies for diseases where methylation is abnormal, such as certain neurological disorders and cancers.
Enzyme Inhibition Studies: SAH is used to study enzymes like SAH hydrolase, which converts SAH to homocysteine and adenosine. Inhibitors of this enzyme are being explored for therapeutic potential in hyperhomocysteinemia (elevated homocysteine) and related conditions.
Methylation Cycle Studies: As part of the methionine cycle, SAH is crucial for understanding the broader impacts of nutrition on cellular metabolism and methylation.
Homocysteine Metabolism: Since SAH is a precursor of homocysteine, its levels are used to study homocysteine-related metabolism, which has implications for health, particularly in cardiovascular and brain health.
In summary, 5'-Deoxy-S-adenosyl-L-homocysteine has applications in research on methylation, disease biomarker studies, drug development, and metabolic research, making it valuable in both laboratory and clinical settings.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide 5'-Deoxy-S-adenosyl-L-homocysteine with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 5'-Deoxy-S-adenosyl-L-homocysteine
Fortunachem Provides Not Only Professional Chemical Products But Also Professional Help
Keeping you up-to-date with all the latest information, news, and events about Fortunachem!
Quick Links
Add:
E-mail:
