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Adapalene is mainly used to improve inflammatory lesions, regulate the differentiation of hair follicles, sebaceous epithelial cells and the treatment of acne.
Adapalene can inhibit the chemical chemotaxis of human multinucleated leukocytes, and can inhibit the metabolism of polymorphonuclear gate singing by inhibiting the transformation of arachidonic acid into inflammatory mediators by lipid oxidation and deficiency, thereby alleviating the inflammatory response mediated by cellular responses. It is suitable for the treatment of acne vulgaris with acne, papules and pustules as the main manifestations. It can also be used to treat acne on the face, chest and back.
Items | Specification | Result |
Appearance | White to off-white crystalline powder | Conform |
Assay | 98%-102% | 99.6% |
Loss on drying | ≤0.5% | 0.25% |
Sulphated ash | ≤0.1% | 0.06% |
Heavy metals | ≤10ppm | <10ppm |
Related substance | Impurity A≤0.3% Impurity C≤0.25% Impurity D≤0.1% Max unknown impurity≤0.1% Total impurities≤0.5% | Conform |
Product parameters | |
Cas number: | 106685-40-9 |
Appearance: | White to off-white crystalline powder |
Purity: | 98%-102% |
Package details: | 100g,1kg/foil bag |
Brand: | Fortunachem |
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