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Betadex sulfobutyl ether sodium is a new type of pharmaceutical preparation excipient, which belongs to a sulfonic acid derivative of anionic highly water-soluble cyclodextrin.
Betadex sulfobutyl ether sodium can be well combined with drug molecules to form non-covalent complexes, improve the stability, water solubility, safety and effectively improve the biological activity of drug molecules, its nephrotoxicity is small, can alleviate drug hemolysis, control drug release rate.
Items | Specifications | Results |
Appearance | White or almost white hygroscopic powder | White amorphous powder |
pH | 5.0~7.5 | 6.34 |
Water | ≤10.0% | 5.70% |
Aerobic Bacteria | ≤1000cfu/g | <10cfu/g |
Molds and yeasts | ≤100cfu/g | <10cfu/g |
Escherichia coli | Should not be detected | Not detected |
Salmonella | Should not be detected | Not detected |
Sulfobutylbetadex sodium | 98.0%~102.0% | 98.76% |
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Product parameters | |
Cas number: | 182410-00-0 |
Appearance: | White or almost white hygroscopic powder |
Purity: | 98~102% |
Package details: | 20kg/drum |
Brand: | Fortunachem |
Betadex Sulfobutyl Ether Sodium (SBECD) is a complexing agent used in pharmaceutical formulations. Its primary application is in the formulation of injectable drugs to improve their solubility and bioavailability. SBECD forms inclusion complexes with certain drugs, enhancing their aqueous solubility and stability, which is particularly useful for drugs with poor water solubility. This can lead to improved drug delivery, better therapeutic outcomes, and sometimes allows for the use of lower doses of the active pharmaceutical ingredient. Additionally, SBECD has been investigated for its potential use in drug detoxification and as a carrier for targeted drug delivery systems.
Solubilizer, wetting agent, chelating agent, taste masking agent.
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