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Anastrozole is an aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women. It works by blocking the enzyme aromatase, which converts androgens into estrogen, thereby reducing estrogen levels that fuel cancer growth. Typically taken as a 1 mg daily pill, it helps prevent cancer recurrence after surgery and controls metastatic disease. Common side effects include hot flashes, joint pain, and fatigue, while serious risks include bone loss (osteoporosis) and elevated cholesterol. It’s not for premenopausal women or pregnant patients. Brand names include Arimidex. Regular monitoring (bone density, cholesterol) is advised during long-term use.
Description of Anastrozole from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Anastrozole | |
Product Name | |
CAS NO. | 120511-73-1 |
Apperance | White or off-white crystalline powder |
Assay | 99.8% |
Pacakge | 1kg/Foil Bag, 25kg/ Box/carton |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Anastrozole CAS 120511-73-1
Items | Specifications | Results |
Appearance | White or off-white crystalline powder | Conforms |
Assay(on dry basis) | 98%~102%(HPLC) | 99.8% |
Heavy metals | NMT 0.001% | <0.001% |
Melting Point | 82.0~85.0℃ | 83.1~83.4℃ |
Water | NMT 0.3% | |
Residue on ignition | NMT 0.1% | 0.04% |
Indentification | IR Reactive | Conform with standard IR Conforms |
Related substance sImpurity B Impurity C Impurity D Impurity E Single Unknown Impurity Total Unknown Impurity Total Impurity |
NMT 0.2% NMT 0.2% NMT 0.1% NMT 0.1% NMT 0.1% NMT 0.2% NMT 0.5% |
0.04% 0.03% 0.02% 0.02% 0.05% 0.08% 0.20% |
Residual solvents Dichloromethane Chloroform Ethanol Cyclohexane Ethylacetate | NMT 0.06% NMT 0.006% NMT 0.5% NMT 0.08% NMT 0.5% |
ND ND 0.05% 0.02% 0.1% |
Conclusion | The product conforms to the Enterprise Standard. | |
Introduction of Anastrozole is an aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women. It works by blocking the enzyme aromatase, which converts androgens into estrogen, thereby reducing estrogen levels that fuel cancer growth. Typically taken as a 1 mg daily pill, it helps prevent cancer recurrence after surgery and controls metastatic disease. Common side effects include hot flashes, joint pain, and fatigue, while serious risks include bone loss (osteoporosis) and elevated cholesterol. It’s not for premenopausal women or pregnant patients. Brand names include Arimidex. Regular monitoring (bone density, cholesterol) is advised during long-term use.
Application of Anastrozole is a prescription medication classified as an aromatase inhibitor. It is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Anastrozole works by blocking the enzyme aromatase, which converts androgens (like testosterone) into estrogen.
By reducing estrogen levels, it helps slow or stop the growth of estrogen-dependent breast tumors.
Breast Cancer Treatment:
Adjuvant therapy: Used after surgery (or other primary treatments) to prevent cancer recurrence.
Metastatic breast cancer: Helps control advanced cancer that has spread.
Off-label uses: Sometimes prescribed for estrogen suppression in fertility treatments or gynecomastia (male breast enlargement).
Standard dose: 1 mg tablet taken once daily, with or without food.
Duration: Typically taken for 5–10 years, depending on cancer risk and doctor’s recommendation.
Common:
Hot flashes, joint/muscle pain, fatigue, mood swings, vaginal dryness.
Serious (less common):
Bone loss (osteoporosis) – Requires monitoring (bone density scans).
Increased cholesterol levels.
Liver dysfunction (rare; blood tests may be needed).
Not for premenopausal women (ovaries still produce estrogen).
Avoid in pregnancy (can harm fetal development).
Caution in patients with:
Osteoporosis or high fracture risk.
Heart disease or high cholesterol.
Severe liver impairment.
Estrogen-containing therapies (e.g., HRT) – May counteract Anastrozole.
Tamoxifen – Reduces Anastrozole’s effectiveness (usually not combined).
Arimidex (original brand), generic versions available.
Effectiveness: Studies show it reduces breast cancer recurrence by ~40% in high-risk postmenopausal women.
Monitoring: Regular check-ups for bone health, cholesterol, and liver function are recommended.
Always take as prescribed and discuss side effects with your oncologist. Anastrozole is a critical medication in hormone-sensitive breast cancer management but requires careful long-term monitoring.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
How do you treat quality complaint ? | |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Anastrozole with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Anastrozole.
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