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Cinepazide maleate is a calcium channel blocker, which relaxes vascular smooth muscle and expands cerebral blood vessels, coronary blood vessels and peripheral blood vessels by preventing Ca2+ from entering the transmembrane of vascular smooth muscle cells, thereby relieving vasospasm, reducing vascular resistance and increasing blood flow. In addition, cinepazide maleate can also enhance the effect of adenosine and cyclic adenosine monophosphate (cAMP) and reduce oxygen consumption; Inhibits cAMP phosphodiesterase and increases the number of cAMP; Improve the flexibility, deformability and ability of red blood cells to pass through capillaries, reduce blood viscosity, improve microcirculation; Improve cerebral blood flow, improve cell nutrition, energy metabolism and anti-ischemia and hypoxia, and protect brain cell function; Inhibits platelet agglomeration, reduces oxygen free radical production, reduces the chemotaxis of neutrophils to vascular endothelial cells, improves the toughness and deformation ability of red blood cells, and reduces blood viscosity, thereby improving microcirculatory perfusion.
Cinepazide maleate is mainly used in the treatment of cardiovascular and cerebrovascular diseases, especially for cerebral arteriosclerosis, transient ischemic attacks, cerebral thrombosis, cerebral embolism, sequelae of cerebral hemorrhage and sequelae of cerebral trauma.
Items | Technical index |
Product name | Cinepazide maleate |
CAS NO. | 26328-04-1 |
Molecular formula | C26H35N3O9 |
Molecular weight | 533.57 |
Appearance | White crystalline powder |
Purity | 99%min |
Product parameters | |
Cas number: | 26328-04-1 |
Appearance: | White crystalline powder |
Purity: | 98.5~101.5% |
Package details: | 1kg/foil bag; 25kg/drum |
Brand: | Fortunachem |
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