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Clindamycin phosphate is a chemically semi-synthetic clindamycin derivative, white or off-white crystalline powder at room temperature, odorless, bitter taste, hygroscopic. There is no antibacterial activity in vitro, and it can be rapidly hydrolyzed to clindamycin after entering the body to exert pharmacological effects. Its mechanism of action, antibacterial spectrum, indications, and therapeutic effect are the same as clindamycin, but its fat solubility and permeability are better than clindamycin, and can be administered orally or intramuscularly and intravenously, mainly metabolized in the liver, excreted through bile and feces, and partially excreted in the urine. Compared with lincomycin, clindamycin phosphate has a strong antibacterial effect of 4~8 times, good absorption, high bone tissue concentration, and strong antibacterial activity against gram-positive cocci and anaerobic bacteria.
Clindamycin phosphate is mainly used for the treatment of tonsillitis, purulent otitis media, sinusitis, acute bronchitis, acute exacerbations of chronic bronchitis, pneumonia, lung abscess, bronchiectasis co-infection, skin and soft tissue infections, etc.
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | White or almost white crystalline powder | Conforms |
PH | 3.5 ~ 4.5 | 3.9 |
Acetone | ≤0.5% | 0 |
Methanol | ≤0.3% | 0 |
Ethanol | ≤0.5% | 0.0251% |
Pyriodine | ≤0.02% | 0 |
Water | ≤6.0% | 1.7% |
Assay | ≥758ug/mg | 836ug/mg |
Product parameters | |
Cas number: | 24729-96-2 |
Appearance: | White crystalline powder |
Purity: | ≥758ug/mg |
Package details: | 25kg/drum |
Brand: | Fortunachem |
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