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Cyclophosphamide is a medication used primarily in chemotherapy to treat various types of cancer. It belongs to a class of drugs called alkylating agents, which work by interfering with the growth and spread of cancer cells in the body. Cyclophosphamide can be administered orally or intravenously.
In addition to cancer treatment, cyclophosphamide is also used in the treatment of certain autoimmune diseases, such as lupus nephritis and rheumatoid arthritis. It works by suppressing the immune system, which can help reduce inflammation and prevent the immune system from attacking healthy tissues.
Like all chemotherapy drugs, cyclophosphamide can have side effects, including nausea, vomiting, hair loss, increased risk of infection, and a decrease in blood cell counts. However, its benefits in treating cancer and autoimmune diseases often outweigh these risks when used appropriately under medical supervision.
Description of Cyclophosphamide from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Cyclophosphamide | |
Product Name | Cyclophosphamide |
CAS NO. | 50-18-0 |
Apperance | White powder |
Assay | 99% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Broad-spectrum anti-tumor API Cyclophosphamide CAS NO 50-18-0 CTX
ITEMS | SPECIFICATIONS | RESULTS | |
Appearance | A white or almost white crystalline powder | Conforms | |
Solubility | Soluble in water, freely soluble in alcohol | Conforms | |
Identification(IR) | IR spectrum is comparing with the spectrum of reference standard | Conforms | |
Appearance of solution | Solution S is clear and not more intensely coloured than reference solution Y6 | Conforms | |
pH | 4.0 ~ 6.0 | 4.23 | |
Chlorides | N.M.T. 330ppm | Conforms | |
Phosphates | N.M.T. 100ppm | Conforms | |
Water | 6.0%~ 7.0% | 6.47% | |
Related substances | Any single impurity N.M.T. 1.0% | Conforms | |
Residual solvents | Dichloromethane | N.M.T. 600ppm | 55ppm |
Acetone | N.M.T. 5000ppm | 102ppm | |
Triethylamine | N.M.T. 5000ppm | Not detected | |
Pyridine | N.M.T. 200ppm | Not detected | |
Assay | 98.0%~102.0%(on anhydrous basis) | 99.21% | |
Conclusion | Conforms to the requirement of EP 10.0 |
Cyclophosphamide has several applications primarily in the fields of oncology (cancer treatment) and rheumatology (autoimmune diseases). Here are some of its key applications:
1. Cancer Treatment: Cyclophosphamide is used to treat various types of cancer, including:
- Leukemia
- Lymphoma (e.g., Hodgkin's lymphoma, non-Hodgkin's lymphoma)
- Breast cancer
- Ovarian cancer
- Lung cancer
- Neuroblastoma
- Multiple myeloma
- Sarcomas (e.g., osteosarcoma, soft tissue sarcoma)
- Retinoblastoma (eye cancer)
2. Autoimmune Diseases: Cyclophosphamide is also employed in the treatment of certain autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. These conditions include:
- Lupus nephritis: Kidney inflammation caused by systemic lupus erythematosus (SLE).
- Rheumatoid arthritis: An autoimmune disorder that primarily affects the joints.
- Vasculitis: Inflammation of blood vessels.
- Wegener's granulomatosis: A type of vasculitis affecting the small and medium-sized blood vessels.
3. Bone Marrow Transplantation: Cyclophosphamide is sometimes used in conditioning regimens prior to bone marrow transplantation to suppress the recipient's immune system and prevent rejection of the transplanted marrow.
4. Other Disorders: In addition to cancer and autoimmune diseases, cyclophosphamide may be used off-label or in experimental settings for conditions such as severe systemic sclerosis (scleroderma), severe aplastic anemia, and refractory immune thrombocytopenic purpura (ITP), among others.
Cyclophosphamide can be administered orally or intravenously, depending on the condition being treated and the treatment protocol established by the healthcare provider. It's a potent medication that requires careful monitoring and management to balance its therapeutic benefits with potential side effects.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Cyclophosphamide with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Cyclophosphamide.
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