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Diethyl ethoxymethylenemalonate is used as an intermediate for chloroquine, norfloxacin and lomefloxacin.
Diethyl ethoxymethylenemalonate is used for synthesis of pyrido[3,2-e]pyrimido[1,2-c]pyrimidines. Initially, it was used to monitor lysine decarboxylase activity. It is useful in the determination of amino acids by precolumn derivatization by using reversed-phase high-performance liquid chromatography (HPLC). It plays an important role in the Gould-Jacobs reaction to prepare quinolines. For example, anile reacts with this reagent to give 4-hydroxyquinoline. It acts as an intermediate in the production of flumequine, which is a fluoroquinolone antibiotic.
Product Name | Diethyl ethoxymethylenemalonate |
Apperance | Colorless liquid |
EINECS | 201-725-7 |
MF | C10H16O5 |
MW | 216.23 |
Assay | ≥99.0% |
Product parameters | |
Cas number: | 87-13-8 |
Appearance: | Colorless liquid |
Purity: | 99%min |
Package details: | 200kg/drum |
Brand: | Fortunachem |
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