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Fexofenadine hydrochloride is used to treat acute or chronic urticaria, allergic rhinitis, insect bite dermatitis, eczema, skin pruritus, etc.
Fexofenadine hydrochloride is a second-generation H1 receptor antagonist that selectively blocks receptors affected by H1 receptors and has good antihistamine effects, but has no anti-serotonin, anticholinergic and anti-adrenaline effects. In addition to the advantages of second-generation histamine H1 receptor antagonists, fexofenadine hydrochloride also has the following advantages: 1) the mechanism of action is clear; 2) Long half-life and long action time; 3) It is not metabolized by the liver, can be safely used in patients with liver function damage, and has no damage to the liver; 4) The characteristics of action are obvious: fexofenadine hydrochloride is effective and well tolerated for allergic rhinitis and chronic spontaneous urticaria, and has a certain inhibitory effect on histamine-induced skin rash and flushing; 5) Few adverse reactions, no cardiotoxicity.
Items | Specifications | Results |
Appearance | White to off white powder or crystalline powder | White crystalline powder |
Loss on drying | ≤0.5% | 0.1% |
Residue on Ignition | ≤0.2% | 0.1% |
Single impurity | ≤0.5% | 0.1% |
Total impurities | ≤1.0% | 0.3% |
Assay | ≥98.5% | 100.4% |
Product parameters | |
Cas number: | 153439-40-8 |
Appearance: | White to off white powder or crystalline powder |
Purity: | 98.5%min |
Package details: | 1kg/foil bag; 25kg/fiber drum |
Brand: | Fortunachem |
Used for acute or chronic urticaria, allergic rhinitis, insect bite dermatitis, eczema, pruritus, etc.
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