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Fluorocytosine is mainly used for mucocutaneous candidiasis, candida endocarditis, candida arthritis, cryptococcal meningitis and coloring fungal diseases.
The inhibitory effect of fluorocytosine on fungi is due to its entry into the cells of sensitive fungi, under the action of cytosine deaminase, deamination to form an antimetabolite—5-fluorouracil. The latter in turn transforms into 5-fluorouracil deoxynucleoside and inhibits thymine nucleoside synthetase, blocks the conversion of uracil deoxynucleoside to thymidine nucleoside, and affects DNA synthesis. It has a good inhibitory effect on Candida, Cryptococcus and Dimiformia, and also has an effect on some Aspergillus, as well as clades and bottle fungi that cause dermatomycosis.
Items | Specifications | Results |
Description | White or almost white crystalline powder | Complies |
Loss on drying | ≤0.50% | 0.23% |
Assay | ≥98.5% | 99.3% |
Product parameters | |
Cas number: | 2022-85-7 |
Appearance: | White or almost white crystalline powder |
Purity: | 98.5%min |
Package details: | 25kg/drum |
Brand: | Fortunachem |
Antifungal and antimicrobial agent.
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