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Iguratimod is an anti-rheumatic agent.
The main mechanism of action of iguratimod is: by selectively inhibiting cyclooxygenase-2, thereby reducing the production of prostaglandins in inflammatory tissues, inhibiting the release of bradykinins in inflammatory tissues, inhibiting antigen-specific T cell proliferation, reducing the level of pro-inflammatory factors produced by B cells in patients with rheumatoid arthritis, stimulating osteoblast differentiation and bone construction, inhibiting synovial cell co-stimulating factor expression and cytokine production. It can inhibit the production of immunoglobulins, inhibit cytokine production, inhibit bone resorption and promote bone formation.
Items | Specifications | Results |
Appearance | White crystalline powder | Complies |
Loss on Drying | ≤0.5% | 0.21% |
Related substance | ≤1.0% | 015% |
Assay | ≥99.0% | 99.85% |
Product parameters | |
Cas number: | 123663-49-0 |
Appearance: | White crystalline powder |
Purity: | 99%min |
Package details: | 100g/bottle; 1kg/foil bag |
Brand: | Fortunachem |
Iguratimod acts as an anti-inflammatory agent, used primarily in the treatment of rheumatoid arthritis.
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