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Imatinib mesylate is used in the treatment of chronic myelogenous leukemia. Imatinib mesylate inhibits Bcr-Abl tyrosine kinase at the cellular level, and can selectively inhibit the proliferation and induction of apoptosis of fresh cells in patients with Bcr-Abl positive cell lines, Ph-positive chronic myeloid leukemia and acute lymphoblastic leukemia. Imatinib mesylate can also inhibit platelet-derived growth factor (PDGF) receptors, stem cell factor (SCF), and tyrosine kinases of c-Kit receptors, thereby inhibiting cell behavior mediated by PDGF and stem cell factors.
Items | Specification |
Product name | Imatinib mesylate |
CAS | 220127-57-1 |
Appearance | White powder |
Assay | ≥98% |
Molecular Formula | C30H35N7O4S |
Molecular Weight | 589.71 |
EINECS | 606-892-3 |
Product parameters | |
Cas number: | 220127-57-1 |
Appearance: | White powder |
Purity: | 99%min |
Package details: | 25kg/drum |
Brand: | Fortunachem |
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