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Isosorbide dinitrate is mainly used for the long-term treatment of coronary heart disease and the prevention of vasospasmodic and mixed angina, and is also suitable for the treatment of myocardial infarction and the long-term treatment of chronic heart failure.
The basic pharmacological effect of isosorbide dinitrate is to directly relax smooth muscle, especially vascular smooth muscle, expand peripheral arteries and veins, reduce the amount of blood returning to the heart, reduce the pre- and post-cardiac load, reduce myocardial oxygen consumption, and have the effect of expanding coronary arteries, which can improve local coronary blood flow and myocardial blood supply in ischemic areas to achieve the purpose of anti-angina.
| Items | Specifications | Results |
| Appearance | White crystalline powder (Undiluted) | Conforms |
| Impurity A | ≤0.5% | 0.09% |
| Impurity B | ≤0.5% | 0.13% |
| Impurity C | ≤0.5% | 0.21% |
| Assay | 36%~44% | 41.2% |
| 95%~105%, stated on the label | 99.97% |
| Product parameters | |
| Cas number: | 87-33-2 |
| Appearance: | Isosorbide dinitrate |
| Purity: | 40% (diluted) |
| Package details: | 1kg/foil bag; 25kg/fiber drum |
| Brand: | Fortunachem |
Used as an antianginal.
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