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Ivermectin is a new type of high-efficiency semi-synthetic antibiotic insecticide, acaricide, nematicide, belongs to insect nerve agent, biological penetrant. The mechanism of action is to interfere with the neurophysiological activities of pests, stimulate the release of γ-aminobutyric acid, act on the nerve-muscle junction, increase the release of chloride ions, inhibit the information transmission of the nerve junction, and lead to paralysis and poisoning death of pests and pest mites. Ivermectin is a new broad-spectrum, high-efficiency, low-toxicity antiparasitic drug, which has a good repellent effect on in vivo and in vitro parasites, especially nematodes and arthropods. However, it is not effective against tapeworms, flukes, and protozoa.
Ivermectin is a good drug for the treatment of mite disease.
| ITEMS | SPECIFICATIONS | RESULTS |
| Appearance | White or yellowish crystalline power | White crystalline power |
| Ethanol | ≤5.0% | 4.3% |
| Formamide | ≤3.0% | 2.7% |
| Heavy metals | ≤0.002% | ＜0.001% |
| Water | ≤1.0% | 0.4% |
| Sulphated ash | ≤0.1% | 0.05% |
| Assay | 95.0-102.0 % | 95.8% |
| Product parameters | |
| Cas number: | 70288-86-7 |
| Appearance: | White or yellowish crystalline power |
| Purity: | 95~102% |
| Package details: | 1kg/foil bag; 25kg/drum |
| Brand: | Fortunachem |
Ivermectin is a widely used antiparasitic medication. It was discovered in the 1970s and its developers won the Nobel Prize in Physiology or Medicine in 2015 for its global impact in reducing parasitic diseases.
Function: It works by paralyzing and killing parasites. It targets the nervous system of invertebrates (like parasites) with minimal effect on humans, making it very safe for its intended uses.
Veterinary Medicine: It is extensively used to prevent and treat heartworm and other parasitic infections in animals (e.g., dogs, horses, livestock).
Human Medicine: In humans, it is FDA-approved at specific doses to treat:
Strongyloidiasis: An intestinal infection caused by the roundworm Strongyloides stercoralis.
Onchocerciasis (River Blindness): An infection caused by the parasitic worm Onchocerca volvulus, which is transmitted by blackflies.
Other Parasites: It is also used for scabies and lice.
It is on the World Health Organization's (WHO) List of Essential Medicines.
During the COVID-19 pandemic, ivermectin gained significant and controversial attention.
Early Hope: Some early laboratory studies in vitro (in a petri dish) suggested it could inhibit the SARS-CoV-2 virus. However, the concentrations required for this effect were far higher than safe and achievable levels in the human body.
Lack of Evidence: Subsequent large-scale, robust clinical trials and major health organizations (including the FDA, WHO, and CDC) found no conclusive evidence that ivermectin is effective for preventing or treating COVID-19.
Dangers of Misuse: This led to warnings against using veterinary formulations or unprescribed human doses, which can be highly toxic and cause serious harm, including nausea, vomiting, seizures, and even death.
| Aspect | Description |
|---|---|
| What it is | A Nobel Prize-winning antiparasitic drug. |
| Approved Use | Effectively treats specific parasitic worm infestations in humans and animals. |
| COVID-19 | Not approved or proven effective for preventing or treating COVID-19. |
| Major Risk | Self-medication, especially with veterinary products, is dangerous and can be lethal. |
In summary, ivermectin is a critically important and life-saving medication for its approved antiparasitic uses, but it is not a proven treatment for viral infections like COVID-19. Its use should always be guided by a medical professional for approved conditions.
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