Name: China Chemical Manufacturer Supply High Quality Levamisole Hydrochloride CAS 16595-80-5 with best price
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Levamisole Hydrochloride CAS 16595-80-5

Item	Specifications	Results
Appearance	White or almost white crystalline powder	White crystalline powder
Heavy Metal	≤20ppm	Conform
PH	3.0 – 4.5	4.0
Sulphate ash	≤0.1%	0.1%
Loss on drying	≤0.5%	0.1%
Assay	98.5% - 101.0%	99.4%

Parameters of Levamisole Hydrochloride CAS 16595-80-5

Product parameters
Cas number:	16595-80-5
Appearance:	White or almost white crystalline powder
Purity:	98.5% - 101.0%
Package details:	1kg/foil bag, 25kg/drum or as you require
Brand:	Fortunachem

Levamisole Hydrochloride is a synthetic compound that was originally developed as an anthelmintic (deworming) medication but is also known for its immunomodulatory properties.

Here is a breakdown of what it is and its key selling points based on its pharmacological profile and market usage:

What is Levamisole Hydrochloride?

Chemical Identity: It is the hydrochloride salt of Levamisole, the left-rotating (S-enantiomer) isomer of tetramisole. Its CAS number is 16595-80-5.

Primary Classification: Broad-spectrum anthelmintic (anti-parasitic) and immune response modifier.

Forms: Available as tablets, injections, topical preparations, and raw pharmaceutical powder.

History: Introduced in the 1960s, it was widely used to treat parasitic worm infections in humans and livestock. While its use in humans has declined in many Western countries due to safety concerns (e.g., agranulocytosis), it remains in use in veterinary medicine and specific human medical protocols in certain regions.

Key Selling Points & Benefits

1. Dual Action: Antiparasitic + Immunomodulation

Unlike standard dewormers that only kill parasites, Levamisole has a unique "selling point" of stimulating the host's immune system.

Anthelmintic Efficacy: It is highly effective against nematodes (roundworms), including Ascaris (roundworm), Ancylostoma (hookworm), and Strongyloides. It works by paralyzing the worms via nicotinic acetylcholine receptor agonism, causing them to be expelled from the body.

Immune Restoration: It restores depressed immune function by enhancing T-cell proliferation, macrophage activity, and neutrophil chemotaxis. This made it historically valuable as an adjuvant therapy in cancer treatment (e.g., colorectal cancer) alongside chemotherapy like 5-FU, although this use is now more restricted.

2. Veterinary Applications (Major Market)

In the veterinary sector, it is a cost-effective and potent solution:

Broad Spectrum: Effective against gastrointestinal roundworms and lungworms in cattle, sheep, pigs, and poultry.

Growth Promotion: By eliminating parasites and potentially boosting immune health, it can improve feed conversion ratios and weight gain in livestock.

Combination Potential: Often sold in combination with other antiparasitics (like albendazole or ivermectin) to broaden the spectrum of activity and delay resistance.

3. Cost-Effectiveness

As an older, off-patent generic drug, Levamisole HCl is significantly cheaper than newer generation antiparasitics or specialized immunotherapies. This makes it attractive for large-scale agricultural use and in developing healthcare markets.

4. Research Utility

In scientific research, it is valued as a specific tool for studying nicotinic acetylcholine receptors (nAChRs) and immune system modulation mechanisms.

Important Safety & Regulatory Context

While these are the functional "selling points," any commercial or medical discussion must acknowledge significant caveats:

Human Safety: In humans, it carries risks of serious side effects, including agranulocytosis (a dangerous drop in white blood cells) and vasculitis. Consequently, its approval for human use has been withdrawn or severely restricted in the US, EU, and many other regions.

Illicit Adulterant: Unfortunately, Levamisole is frequently found as an adulterant in illicit cocaine supplies (acting as a cutting agent), which has led to severe public health issues (e.g., necrotic skin lesions in users). This is a negative association rather than a selling point but is crucial for context.

Veterinary Withdrawal Periods: In food-producing animals, strict withdrawal periods must be observed before slaughter to ensure no residues remain in meat or milk.

Summary

The primary value proposition of Levamisole Hydrochloride lies in its dual capability to clear parasitic infections while simultaneously boosting immune response, all at a low cost. Today, its legitimate market is predominantly in veterinary medicine and specific research applications, rather than general human medicine.