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The antibacterial mechanism of levofloxacin hydrochloride is mainly to inhibit bacterial DNA cyclotronase and topoisomerase IV, inhibit the synthesis and replication of bacterial DNA and achieve the purpose of sterilization, which has the advantages of strong antibacterial effect, wide antibacterial spectrum, good oral absorption, long action time, wide distribution in vivo, high tissue concentration, no cross-resistance with other antibacterial drugs and few and mild adverse reactions. Levofloxacin hydrochloride is mainly used for the treatment of upper and lower respiratory tract infections, intestinal infections, genitourinary tract infections and skin and soft tissue infections caused by sensitive bacteria, and can also be combined with other antibacterial drugs to eradicate Helicobacter pylori.
Levofloxacin hydrochloride is an artificially synthesized antibacterial drug, which has the characteristics of a wide antibacterial spectrum and strong antibacterial effect.
| Items | Specifications | Results |
| Appearance | Off-white or light yellow needle crystalline powder | Light yellow needle crystalline |
| Specific rotation | -47°~-52° | -50° |
| Opticalisomer | ≤1.0% | 0.32% |
| pH value | 3.5~5.0 | 3.9 |
| Related substances | ≤0.50% | 0.07% |
| Loss on drying | ≤5.0% | 2.7% |
| Residue on ignition | ≤0.2% | 0.03% |
| Heavy metals | ≤20ppm | ＜20ppm |
| Assay | ≥89.5% | 90.4% |
| Product parameters | |
| Cas number: | 177325-13-2 |
| Appearance: | Off-white or light yellow needle crystalline powder |
| Purity: | 89.5%min |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
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