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Sorafenib tosylate is used to treat liver, kidney, and thyroid cancers. Sorafenib tosylate has a dual anti-tumor effect: it can directly inhibit the proliferation of tumor cells by blocking the cell signaling pathway mediated by RAF/MEK/ERK, and can also block the formation of tumor neovascularization by inhibiting VEGF and platelet-derived growth factor (PDGF) receptors, and indirectly inhibit the growth of tumor cells.
Items | Specification | Result |
Assay | ≥99.0% | 99.31% |
Appearance | Off white to white crystalline powder | Off white crystalline powder |
Loss on drying | ≤0.5% | 0.03% |
Residue on ignition | ≤0.5% | 0.31% |
Each related substances | ≤0.5% | Complies |
Product parameters | |
Cas number: | 284461-73-0 |
Appearance: | Off white to white crystalline powder |
Purity: | 99%min |
Package details: | 1kg/foil bag |
Brand: | Fortunachem |
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