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Streptozocin is an N-nitroso-containing compound that acts as a donor of nitric oxide in the pancreatic islets.
It is a compound containing N-nitroso ,it acts as a nitric oxide donor in pancreatic islets ; it can induce the death of diabetic animal model style of insulin-secreting cells . Efficient DNA methylation agent, can induce chromosome breakage. It has cell toxicity On the neuroendocrine tumor cell lines with the expression of GLUT2 glucose transporter (GLUT2 glucose transporter) . Streptozocin is used for inducing Type 1 diabetes in Medical researches .
Items | Specifications | Results |
Appearance | Pale yellow crystalline powder | Conforms |
Water | ≤3.0% | 0.35% |
Assay | ≥98.0% | 99.8% |
Product parameters | |
Cas number: | 18883-66-4 |
Appearance: | Pale yellow crystalline powder |
Purity: | 98%min |
Package details: | 100g/bottle; 1kg/foil bag |
Brand: | Fortunachem |
Its use is generally limited to patients whose cancer cannot be removed by surgery. In these patients, streptozotocin can reduce the tumor size and reduce symptoms (especially hypoglycemia due to excessive insulin secretion by insulinomas).
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