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Terbinafine hydrochloride is a broad-spectrum antifungal drug used in dermatology. It can specifically disturb the late biodegradation of fungal sterols, selectively inhibit the activity of fungal squalene cyclooxidase, and hinder the reactivation of squalene in the process of fungal cell membrane formation, thus reaching the effect of killing or inhibiting fungi. TeTerbinafine hydrochloride is suitable for the treatment of cutaneous candidiasis, such as tinea manuum, tinea pedis, tinea femoritis, tinea corporis, and tinea versicolor, and is also the best medicine for the treatment of nail fungus.
Terbinafine hydrochloride is a systemic antifungal treatment drug, which has the advantages of rapid sterilization, strong bactericidal effect and accurate therapeutic effect, and has been widely used in the treatment of infectious diseases caused by fungi. The combination of terbinafine hydrochloride tablets and butenafine cream in the treatment of dermatophytosis has an ideal therapeutic effect, can shorten the time for the disappearance of symptoms, and has a certain safety, which is conducive to reducing the risk of recurrence and can be used as a new direction for the treatment of the disease.
Items | Specification | Result |
| Assay | 99%~101%(dried substance) | 99.85% |
| Appearance | White or almost white powder | White powder |
| Loss on drying | ≤0.5% | 0.12% |
| Sulphated ash | ≤0.1% | 0.02% |
| Residual solvents | Acetone ≤0.5% Ispropanol ≤0.5% MIBK ≤0.06% | Not detected 0.005% Not detected |
| Related substances(HPLC) | Impurity A ≤0.1% Impurity B ≤0.1% Impurity C ≤0.1% Impurity D ≤0.1% Any other impurity ≤0.1% Total Impurity ≤0.3% | 0.002% 0.03% 0.03% 0.03% 0.02% 0.15% |
| Product parameters | |
| Cas number: | 78628-80-5 |
| Appearance: | White or almost white powder |
| Purity: | 99%~101% |
| Package details: | 1kg/foil bag;25kg/drum |
| Brand: | Fortunachem |
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