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Tropisetron hydrochloride is used to prevent nausea and vomiting caused by chemotherapy and radiation therapy on tumors. Tropisetron hydrochloride is a potent and highly selective competitive antagonist of peripheral neurogens and serotonin 3 (5-HT3) receptors in the central nervous system. Tropisetron hydrochloride inhibits the gag reflex primarily by selectively blocking the presynaptic 5-HT3 receptors of peripheral neurogens, and its antiemetic effect may also be related to its stimulating effect on the vagus nerve that inhibits the final zone by direct blockade of central 5-HT3 receptors.
Items | Specifications | Results |
Appearance | White crystalline powder | Conforms |
Assay | ≥99% | 99.45% |
Loss on drying | <0.5% | 0.20% |
Residue on ignition | <0.2% | 0.16% |
Product parameters | |
Cas number: | 105826-92-4 |
Appearance: | White crystalline powder |
Purity: | 99%min |
Package details: | 100g/bottle; 1kg/foil bag |
Brand: | Fortunachem |
Used to prevent nausea and vomiting caused by chemotherapy and radiotherapy.
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