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Zolmitriptan is used for the acute treatment of migraine with or without aura symptoms. Zolmitriptan is a highly effective, specific drug for the treatment of acute migraine, which relieves the onset of migraine by stimulating 5-HT1 receptors to cause vasoconstriction and inhibit the release of neuropeptides. Zolmitriptan can control blood flow around the brain and can also act on the pain center of the brain, thus playing a role in the treatment of migraine. Zolmitriptan can penetrate the blood-brain barrier, has the dual role of central and peripheral nerves, selectively contracts intracranial blood vessels, especially cranial arteries, and controls peripheral blood flow to the brain. It can also inhibit the release of vasoactive substances such as CGRP, neurotransmitters A and P, constrict dural artery vasoconstriction, and reduce aseptic inflammation.
| Items | Specification | Result |
| Assay(by Titrate) | 99%-101% | 99.35% |
| Appearance | White to off-white powder | Off-white powder |
| Melting point | 136-141℃ | 137.4-139.5℃ |
| Loss on drying | ≤0.5% | 0.38% |
| Residue on ignition | ≤0.1% | 0.004% |
| Heavy metals | ≤10ppm | <10ppm |
| Substance by HPLC | Single biggest impurity≤0.5% Total impurities≤1.0% | 0.16% 0.35% |
| Product parameters | |
| Cas number: | 139264-17-8 |
| Appearance: | White to off-white powder |
| Purity: | 99%-101% |
| Package details: | 10g,100g,1kg/foil bag |
| Brand: | Fortunachem |
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