Leflunomide CAS 75706-12-6 for sale
Leflunomide CAS 75706-12-6 for sale
Leflunomide CAS 75706-12-6 for sale
Leflunomide CAS 75706-12-6 for sale

Leflunomide CAS 75706-12-6 Wholesale & Bulk

Leflunomide has an immunosuppressive and anti-inflammatory effect and is used in the treatment of active rheumatoid arthritis in adults.

Leflunomide is rapidly converted into active metabolites by the cytoplasm and microsomes of the liver and intestinal wall, and its mechanism of action is mainly to inhibit the activity of a key enzyme in the DNA synthesis process - dihydroorotic acid dehydrogenase (DHODH), so that the nucleotides in B lymphocytes are depleted, the biosynthesis of DNA and RNA is terminated, so that the cells cannot enter the S phase, and eventually can not proliferate, thereby producing anti-rheumatic effects, suitable for the treatment of adult active rheumatoid arthritis, ankylosing spondylitis, May slow bone destruction and reduce signs and symptoms. In addition, leflunomide can also inhibit the activity of tyrosine kinase, thereby inhibiting the proliferation of T cells, B cells and non-immune cells, and can also exert anti-inflammatory effects by inhibiting the synthesis of prostaglandins by inhibiting the biosynthesis of cyclooxygenase-2 (COX2), and can inhibit the release of histamine in mast cells and basophils.

Specifications of Leflunomide CAS 75706-12-6

ItemsSpecification
Product nameLeflunomide
CAS75706-12-6
AppearanceWhite crystalline powder
Assay≥99%
Molecular FormulaC12H9F3N2O2
Molecular Weight270.21
EINECS616-254-6


Parameters of Leflunomide CAS 75706-12-6

Product parameters
Cas number:75706-12-6
Appearance:White crystalline powder
Purity:99%min
Package details:100g,1kg/foil bag
Brand:Fortunachem


Our Packages of Product CAS 75706-12-6 : 100g,1kg/foil bag Wholesale

Our Packages of Product CAS 75706-12-6 : 100g,1kg/foil bag

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