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Nitrendipine has a significant and long-lasting hypotensive and vasoconstrictive effect. It is suitable for various types of hypertension, such as primary and secondary mild and moderate hypertension, and can also be used for coronary heart disease and congestive heart failure.
Nitrendipine can selectively act on the calcium channels of vascular smooth muscle, inhibit the transmembrane calcium ion influx of vascular smooth muscle and myocardium, have a greater affinity for blood vessels than for myocardium, and have a stronger selective effect on coronary arteries. Nitrendipine reduces myocardial oxygen demand and has a protective effect on ischemic myocardium. It can reduce the total peripheral resistance and reduce blood pressure.
Items | Specification | Result |
Assay | 98.5%-101.5% | 99.5% |
Appearance | Yellow crystalline powder | Conform |
Loss on drying | ≤0.5% | 0.1% |
Residue on ignition | ≤0.1% | 0.09% |
Related substance | Impurity A≤0.1% Impurity B,C≤0.8% Total impurity≤1.2% | 0.002% 0.05% 1.0% |
Product parameters | |
Cas number: | 39562-70-4 |
Appearance: | Yellow crystalline powder |
Purity: | 98.5%-101.5% |
Package details: | 100g,1kg/foil bag |
Brand: | Fortunachem |
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