English 
Español 
français 
العربية Search
Search
Perindopril erbumine is used to treat conditions such as hypertension and congestive heart failure.
Perindopril erbumine is an inhibitor of an enzyme that converts angiotensin I to angiotensin II (angiotensin-converting enzyme). This invertase or kinase is a peptide chain terminal lyase that converts angiotensin I into angiotensin Il, which constricts blood vessels, and it also degrades bradykinin, which relaxes blood vessels, into inactive heptapeptides. Inhibition of angiotensin-converting enzyme leads to a decrease in angiotensin II in plasma, which can lead to increased plasma renin activity (by inhibiting negative feedback of renin release) and reduce aldosterone secretion. Because angiotensin-converting enzyme inactivates bradykinin, angiotense inversion inhibition also increases the activity of the circulating and local kallikrein-kallin system (and thus the prostaglandin system).
| Items | Specifications | Results |
| Appearance | White or almost white crystalline powder, slightly hygroscopic | Conforms |
| Impurity A (TLC) | ≤ 0.25% | Conforms |
| Stereochemical purity | Impurity I: ≤0.1% | 0.08% |
| Any impurity ≤0.1% | Not detected | |
| Water (KF) | ≤1.0% | 0.16% |
| Sulphated ash | ≤0.1% | 0.06% |
| Heavy metal | ≤20ppm | Conforms |
| Assay (By titrimetry) | 99.0%~101.0% (on anhydrous basis) | 99.6% |
| Product parameters | |
| Cas number: | 107133-36-8 |
| Appearance: | Off-white to white crystalline powder |
| Purity: | 98%min |
| Package details: | 1kg/foil bag; 25kg/drum |
| Brand: | Fortunachem |
Used for the treatment of high blood pressure, congestive heart failure and other diseases.
Fortunachem Provides Not Only Professional Chemical Products But Also Professional Help
Keeping you up-to-date with all the latest information, news, and events about Fortunachem!
Quick Links
Add:
E-mail:
