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Trabectedin is used in the treatment of inoperable or specific advanced soft tissue sarcomas. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to small grooves in DNA, blocks transcription of stress-induced proteins, induces DNA backbone lysis and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells.
Items | Specifications | Results |
Appearance | White or off-white powder | Conforms |
Assay | ≥98.0% | 99.15% |
Product parameters | |
Cas number: | 114899-77-3 |
Appearance: | White or off-white powder |
Purity: | 98%min |
Package details: | 1g/vial; 10g/PE bottle |
Brand: | Fortunachem |
A tetrahydroisoquinoline alkaloid with antitumor activity isolated from the Caribbean tunicate, Ecteinascidin turbinata.
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