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Captopril is a synthetic non-peptide angiotensin-converting enzyme inhibitor that acts primarily on the renin-angiotensin-aldosterone system (RAA system). Inhibits angiotensin-converting enzyme (ACE) of the RAA system, prevents angiotensin I conversion or angiotensin II, and can inhibit aldosterone secretion and reduce sodium and water retention.
As an antihypertensive drug, captopril has a significant antihypertensive effect on many types of hypertension, and it can also improve the heart function of patients with congestive heart failure.
Items | Specifications | Results |
Appearance | White to off-white crystalline powder | Complies |
Melting range | 104~110℃ | 106~107℃ |
Specific rotation | -125 ~ -134° | -128° |
Loss on drying | ≤1.0% | 0.03% |
Sulphated ash | ≤0.2% | 0.15% |
Heavy metals | ≤0.003% | Complies |
Assay | 97.5%~102.0% | 99.1% |
Captopril disulfide | ≤1.0% | 0.12% |
Product parameters | |
Cas number: | 62571-86-2 |
Appearance: | White to off-white crystalline powder |
Purity: | 97.5%~102.0% |
Package details: | 25kg/drum |
Brand: | Fortunachem |
As an antihypertensive agent, has a markedly antihypertensive effect on various types of hypertension and improves heart function in patients with congestive heart failure.
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