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Estriol is used for leukopenia, various menstrual diseases, senile vaginitis, menopausal syndrome in women, etc.
Estriol has a stronger effect on vaginal epithelial keratinization than estradiol, and can promote vaginal epithelial hyperplasia, superficial cell keratosis, mucosal angiogenesis and vaginal epithelial injury healing; At the same time, estriol can enhance the function of cervical cells, proliferate cervical muscle fibers, and increase cervical elasticity and flexibility.
Items | Specifications | Results |
Appearance | ||
Identification | A:IR B:UV | |
Completeness of solution | The solution is clear and free from undissolved solid. | Conforms |
Solubility | Soluble in acetone,in chloroform,in dioxane,in ether and in vegetable oil,sparingly soluble,in ethanol,insoluble in water | Conforms |
Melting point | About 280℃ | 279.2-281.0℃ |
Loss on drying | 0.12% | |
Specific rotation | +54°~ +62° | +56.4° |
Residual on ignition | 0.04% | |
Related substances Total impurities | ≤2.0% | 0.63% |
Residual solvents: Methanol Acetone Methylene chloride | ≤3000ppm ≤5000ppm ≤600ppm |
161 ppm 122 ppm Not detected |
Assay | 97.0~102.0% | 99.66% |
Micron | 100%≤20um | |
Conclusion | The product complies with the enterprise standards. | |
| Product parameters | |
| Cas number: | 50-27-1 |
| Appearance: | White or practically white ,odorless powder |
| Purity: | 97.0%~102.0% |
| Package details: | 1kg/bag;25kg/drum |
| Brand: | Fortunachem |
Low Potency: Its biological activity is significantly weaker than estradiol (the most potent estrogen). This means it typically has milder effects on tissues like the uterus, reducing certain risks associated with stronger estrogens.
Pregnancy Link: During pregnancy, estriol levels rise dramatically (often 1,000x higher than non-pregnant levels). For this reason, it was historically used to monitor fetal health and placental function.
Localized Action: It is often administered topically (e.g., creams, gels) in clinical settings, as this delivery method focuses its effects on specific tissues (like the vaginal lining) rather than causing widespread systemic changes.
Menopausal Symptom Relief: It is commonly used to treat vaginal symptoms of menopause, such as dryness, itching, or pain during intercourse. Its low potency makes it a preferred option for women who cannot use stronger estrogens (e.g., those with a history of certain cancers).
Urinary Tract Health: It may help reduce the risk of recurrent urinary tract infections (UTIs) in postmenopausal women by improving the health of the urinary tract lining.
Research & Monitoring: In addition to its clinical uses, estriol levels (especially in urine or blood) were once a key marker in prenatal care to assess fetal well-being.




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